These large tablets are not the easiest of things to swallow. Aside from that I have experience no negative effects from taken them. The noticable effect of glucosamine varies a great deal from person to person depending on the state of their joints. A high proportion of people will percieve no benefit, but it is worth persisting with for at least two months as for some users it can be quite effective. I am at the stage where I am just starting to suffer severe joint problems from wear and tear. Since I will be adjusting my lifestyle as well, I don’t want to comment to much on how I percieve any benefits in the short term. As with taking an A-Z vitamin supplement, I am adopting a precautionary attitude rather than assuming any certain benifits. I am trying a high dose in part to match my large skeleton. My intention is to lower the dosage after a period of time, if I decide that they are worth carrying on with.Chondroitin is usually recommended to be taken with glucosamine. The problem with taking both in the same tablet is that researchers have found that many such combined products in fact contain little or no chondritin, and product price cannot be used as a guide of quality. Another issue with chondritin is that its effectiveness has now been downgraded to a marginal benefit at most. Chondritin is an animal derivitive which could also be a reason for some not wishing to take it. Combined products are more likely to contain dangererous contaminants and additives. There are other brands of 1500mg sustained release Glucosamine that are suspiciously charging exactly the same amount for it. It is even more clear that over pricing is taking place, when it is much cheaper to be taking two 1000mg tabs of sustained release glucosamine than it is to take one 1500 mg tablet. The coating also seems to be extraordiarily expensive when you consider how cheap ordinary glucosamine is, so sustained release needs to perform considerably better and I doubt it is that much more effective. An acceptable product, but you will pay through the nose for it.
Ive been lifting weights and recently ive been getting aches around my body its not a muscle issue but more of a joint pain, niggles in my shoulder and back. I thought i’d give this a go to help lubricate things. I know as a scientist that which i natural is always better and im never very confident using pills but ive not had any niggle for the last 2 weeks it may just be that my form has been very or things have healed for now or it could be these tablets.
- L. Brown
I take Glucosamine tablets on a daily basis as I have been having problems with my knees over the last couple of years and I feel that the tablets definitely help. I have just switched over to these Flexable Sustained Release tablets, so it is possibly too early to say if they will have a significantly different effect on how my knees feel but so far they have not had a derogatory effect compared with the last tablets I was taking. One slight negative is that these are quite big and chunky tablets to swallow.
-P. A. Smith
Very difficult to review a product of this sort and comment upon its efficacy. But I would have to say that I do think that I have witnessed an improvement in my joints. This is particularly true of the joints in my legs which have, from time to time, given me some pain. During the period of taking these I have experienced such pain much less frequently. I am not aware that I have changed anything else – I still walk the dog longish distances on a regular basis and when I am at work I move from building to building so get in quite a lot of walking that way too. And I don’t experience any discomfort on my occasional use of the cross trainer. I think I will now purchase another month’s supply to extend the test.The tablets are big and apparently have a slow release coating which means that the Glucosamine is released over a twelve hour period which seems very sensible. I am only holding back one star just because I cannot be 100% sure that the improvement I have noticed is down to the tablets.
My doc was happy with me when I told him I was taking glucosamine to combat my arthritis, so the core product has medical approval. I like the idea of controlled release, which I have only seen on ibruprofen before, as it means I am getting dosage spaced out and not one hit that can pass through the gut and maybe you lose content in bodily waste rather than absorb it all for its benefits. *I have had mixed success with swallowing – the tablets are large and I do not always manage to get one down. If you don’t succeed immediately, it is a struggle, as the pills are not coated. But I get the same problem with my usual brand (well-known High Street retailer). Do they work? – impossible to tell as the single subject in the trial, but my arthritis came on fast when I stopped eating seafood several years ago so I have belief I should have been taking supplements. Now I am trying to manage the condition, so tablets as well as diet are my hope for an active life.
I’ve been using Glucosamine, in various forms, off and on for almost a decade due to miscellaneous wear and tear, mainly on my knees and mainly self-inflicted. First off the package contains 30 fairly large tablets containing 1500mg of slow release Glucosamine Hydrochloride. Now, I’ve mainly used Glucosomine Sulphate in the past and any of my reading from several years ago has suggested that there’s not much difference between the two. Obviously the debate still rages about how efficacious Glucosamine is for protecting, and repairing, joint function but I’m firmly in the camp of the believers, noticing the difference after a few days without.
The other unique selling point here is the sustained release formula. I’ve not read anything that suggests I’d personally benefit from this, over taking a standard 1500mg tab once a day, but this will come down to the advice of your health professional. For me, there’s no reason I would pay a premium for the sustained release formula.
Compared to other, similar if not comparable products it seems expensive but it appears to be a quality product which I was able to take with the help of a glass of water and which caused me no stomach distress – something I did have with another brand many years ago.
3.5 out of 5.
Joint pains can occur at any age ,but traditionally associated with ageing , and can vary in intensity from irritating to severe in the case of osteoarthritis . One treatment has been the use of glucosamine and or chondroitin supplements to ameliorate symptoms.Glucosamine is a naturally occurring substance in the body involved in the generation and maintenance of joint membranes . Currently it is extracted from shellfish ( so avoid if subject to any shellfish allergies) Delivery form – Whilst the product is usually associated with Chondroitin sulphate for controlled release – these tablets are lozenge shaped , coated slow release tablets – to be taken with water and food. Because of the coating they must be swallowed whole ( do not chew or crush the tablets or slow release may be lost). The shape of the tablet makes this easier. The chondroitin formulations are usually more expensive. Target patients – This is not a medicine but a dietary supplement . One might expect it to work best with those with a dietary deficiency or failure to produce adequate supplies in the body. Anyone with joint pains might try it but glucosamine has been successfully used to alleviate symptoms in arthritic patients who have problems with taking NSAIDS (Non steroidal anti inflammatory drugs (There is literature – see Wikipedia – suggesting that it is NOT recommended for problems with knee joints) Suitability for diabetics -As this contains a sugar (glucose) group one might expect possible problems .There is still confused literature , but the latest views suggest NO negative problems BUT it is advisable restrict the dose to one tablet per day and monitor sugar levels as normal. I am diabetic and so far a 1500mg daily dose has no effect on blood sugar levels. I have taken the tablets midday with lunch to avoid conflict with other morning/evening medications. Time to achieve results – This varies from person to person – depending as to whether there was a deficiency in the first place – some literature claims NO positive results. In my experience the tablets are not showing any immediate effect ( after 5 days) – positive or negative .I will update this review after a months trial .Check other reviews where a trial of at least 2 months has been carried out. Worth considering trial if you have joint pains.
I normally take glucosamine sulphate 1500mg as I suffer from some joint pain and am fairly active sportwise so want to be proactive in maintaining my health. These slow release tablets were bigger than I’m used to but I swallowed them with food without difficulty. I didn’t notice any discernible different when using these slow release tablets. That’s not to say they don’t have an effect but when I consider how much more expensive these are I’m going to stick with my original tablets.
I get quite stiff joints in winter so I was keen to try these. I have never tried Glucosamine before, but have heard good things. I’ve been on these around a fortnight and I have felt less stiffness which is positive, I can’t say it’s dramatic and life changing. I hope with taking them longer the improvements will be greater. If anyone has issues swallowing tablets steer well clear, these are huge ones.
Hard to review, in a short period of time, tablets like this. Hard to identify and quantify their benefit as that will be long term and based on on-going usage. Having said that I can comment of the ‘user experience’. These are oblong and quite chunky tablets, not that easy to swallow I have to say (and I am quite good at swallowing tablets) but they do have no noticable aftertaste. Have to say I probably prefer the tablets that have a soft gelatine case as they are easier to swallow.
One pack of these Flexable Glucosamine Tablets lasts for a month, as the stated dose is one tablet per day. I haven’t been taking them for a full month yet but I have already noticed a difference in my joint mobility. I have a knee problem, caused by trauma to the knee, and it often aches. However, since I started these tablets, I have noticed that the aches and pains in my knee have decreased.The tablets are sustained release: they supply your joints with glucosamine for up to 12 hours, so I choose to take my daily dose in the morning, so as to ensure that my knee is being “fed” throughout the day. I am very happy with the results and it will be interesting to see how my knee feels when I have used up this pack of tablets (I’ll edit my review in a few weeks). If it starts aching again nearly every day, then I will continue taking glucosamine, but probably not this brand as the price is expensive in comparison with other brands on the market.
-San Diego Surfer
I’ve been taking glucosamine for a few months now: I do yoga and had noticed my knee joints starting to ache after sessions – these really do make a difference. The tablets are huge but slip down relatively easily. The drawback, of course, is the price: at the current level they’re just over 50p a tablet. Anyone with serious medical conditions may want to take the recommended one tablet a day, but I take one every three or so days and that seems to work perfectly for my mild, exercise-related aches.
I have been taking these for two weeks now and can honestly say that I’m no longer suffering from the joint pain in my knees and ankles that I used to. Although these tablets are large and therefore a tad difficult to swallow, they are a lot more convenient than trying to eat a selection of oily fish and seafood each day. And the ‘sustained release’ feature means that one’s body is constantly getting the supply it needs. Try that with fish! However, I’m giving the product four stars rather than five because I think there should be a clear and prominent warning on the front of the packet. Anyone with an allergy to fish or seafood should not take these tablets. This advice is written on the leaflet inside the packet, but a customer could easily miss this. By the way, for coeliacs like myself there is no problem: the tablets are gluten free.
-The Old Grey Witch's Test
Gluosamine is generally thought to be a supplement that can promote joint flexibility and health (although evidence is not conclusive). These high dose gluosamine tablets are lozenge shaped large tablets but I found them easy to swallow and had no problems taking them. They are designed to deliver a sustained release of glucosamine over a 12 hour period, if swallowed whole to maintain the special coating that helps deliver the gradual release. Without a controlled trial of these tablets, I can’t personally comment on their effectiveness but I had no problems taking them so expect the active ingredient to be as effective or more effective than any other standard tablet. They are very expensive and standard glucosamine tablets can be purchased for the same price as these and yet give a whole year supply rather than just the month supply in this pack. The ingredients are shellfish based, so obviously unsuitable for vegetarians/vegans or those with fish allergies.
I am firmly of the opinion that at 70 mum should take all she can front the JOINT brigade of tablets, as its around 75 when the aches and pains kick in a little and its best to get ahead with all the help to hand-so I shall report back-the electronic Foot vibrating pad from last year was fabulous for a stiff knee joint so here goes hopefully for another test to report back on.
-Avid British Reader
My wife takes glucosamine tablets to help with her arthritis, so we were very pleased to get these to review. The tablets come in foil blister packs, and are quite large but easy to swallow. They are tasteless and so very easy to take. We think the only downside to these tablets, as the cost. We normally buy supplements from HEALTH SPAN and at a much lower cost. Because of the forecast cost, we have only given these three stars.
Have used this before and it can make a difference to your joints movement with prolonged use. I think you need to try it for at least a month and then decide if it has improved notability. All these supplements are costly but if they work for you then it is well worth continuing with.
My mother (65 yo) has for a longer while problems with her ankles: they are painful and getting swollen from time to time when she walk too much but according to the doctors there is no particular reason for this, except for tear & wear. The Flexable tablets state to help lubricate the joints, reduce joint inflammation and swelling and keep joints able to flex so I asked her to try those pills and after only a week of use she swears there is difference… I can’t say for sure that the pills work it could be more of a placebo effect, but whatever it is – it works. What I can confirm (as we live together) is that she does not take painkillers all the time anymore and in the morning it takes her less time to start moving around the house, which is great improvement! Additional plus is that the tablets are "sustained release" what means the medicine is released to the body slowly for extended period of time (12 hours) so it last longer and need to be taken only once a day. Also (from our experience) the Flexable tablets do not cause any side effect or unpleasant sensations like heartburn, when some other similar tablets do. It is still early days but for now we are giving Flexable 5 * as there is absolutely nothing bad to say about this product. If anything will change after couple of months of use I will update this review accordingly.
-Coffee & Vanilla
Glucosamine sustained release:
Glucosamine is a food supplement that is thought to help with joint problems including arthritis. There is a lot of research about it online and polarised opinions of it’s effectiveness. It is also used to treat joint problems in older horses. We use an animal grade supplement containing Glucosamine on one of our older horses and it has worked wonders for him.
Seeing the results from the horse Glucosamine and having a few joint problems myself I decided to take it as well. My usual supply comes from Simply Supplements but I was happy to try this slow release version. The Simply Supplements had Chondroitin in it as well but this version from Amazon has only Glucosamine. Early days:
I have taken this is place of my normal supplement for two days. My joints seem fine and no clicking when getting out of the bed. I have put in a hard days work on my small holding today with lots of lifting and climbing and no joint pain. I can conclude that this supplement is as good as my regular one. Slow release:
I take the tablet in the morning as directed and I am sure it is giving me a sustained release which must be a benefit. I can also report no stomach problems while taking this. I’ll report back after using these for two weeks when I have more data. Overall:
This seems a good product. The pack contains plenty of information about the product and a data sheet on it. I know that Glucosamine supplements work as I do feel much more supple and get much less joint pain than when I did not take it. I have researched it on the net and on balance think it is a worthwhile supplement to help with joint care. This product seems well produced and I will report back after I have been on it for a few weeks. Then I will have a better idea on how it compares to the pervious product I was taking.
- RJP the Book Boy
I take a Glucosamine and Chondroitin mix for arthritis, so thought I’d give these a whirl. Unfortunately within 3 days I realised they weren’t working. For me, there are two possibilities:
- These suggest they are one a day tablets, but the other ones I take have the same amount of glucosamine but are three times a day (although I take two).
- They need the other supplements to be effective – chondroitin is recognised as an important element, and I also have some ginger and other trace elements (eg manganese) in what I take now.
- The Dunelmian
I’ve been using glucosamine and cod liver oil tablets, or glocosmine sulphate for a little under three years, bought from Holland and Barret. I began suffering from aches in the heel of my right foot, to the point of becoming painful, and occasionally in my pelvic bones. My GP put it down to wear and tear; getting older and suggested glucosamine as being something that might help – and it did.Please be careful if you’re considering taking these and don’t exceed the daily dose as there are side effects to excessive use, including developing diabetes. I must admit, since taking glucosamine the aches and pains have been greatly reduced. I’ve no doubt the sustained release tablets will have the same effect, but I won’t be buying them as they’re far too expensive. I can only award 2 stars based on poor pricing. Amazon are selling Glucosamine Sulphate (my normal choice) 1500mg x 360 tablets ( a years supply) for £1 less than this one months supply….
- Ian Wantling
According to Wikipedia glucosamine appears to be safe for use as a dietary supplement; effectiveness has not been established for any condition. It’s one of the most common non-vitamin, non-mineral, dietary supplements used by adults. People use it to support the structure and function of joints and it’s marketed to people with osteoarthritis.Glucosamine is often sold in combination with other supplements that aim to help joints but this Flexable Sustained Release Glucosamine seems to simply be a big dose of Glucosamine Hydrochloride in 1500mg tablets – the maximum recommended dose. According to a Universite Laval study, researchers found that in excessive doses glucosamine may damage pancreatic cells, possibly increasing the risk of developing diabetes. According to Wikipedia you shoudn’t combine Glucosamine with chondroitin if you’re treating osteoarthritis – I guess this means you should do your research before deciding which tablet might help the condition you’re trying to alleviate. It’s possible, and you really need to make your own mind up about this, that people find they take more than the recommended dose because they don’t see the results they expected. Some well-conceived research has shown it simply has a placebo effect. Anyway… how much research are you going to do to figure out whether you want to take it? If, like me, you suffer joint pain, then you do whatever you can to keep your joints mobile, even if some of these things may be placebos. The big question is whether you should buy this Flexable product or some other formulation of Glucosamine. Do you think that sustained release is a real benefit? Do you want to mix your glucosamine with some other supplements for some kind of perceived benefit? The answer may come down to cost. A quick bit of searching on Amazon throws up a huge range of options, some the same kind of cost, some dramatically cheaper. There is one company selling 1500mg Glucosamine Sulphate tablets (might not be sustained release) in packs of 360 – a whole years supply for £1 less than this one month supply of Flexable Glucosamine Hydrochloride. The only reason you’d pay more is if you thought there was a quality benefit by choosing Flexable’s product. Unfortunately I think you would need to perform a large scale pharmaceutical trial to reveal the answer to this question.
- M. Williams